Rapid repair of human disease-specific single-nucleotide variants by One-SHOT genome editing

Many human diseases ranging from cancer to hereditary disorders are caused by single-nucleotide mutations in critical genes. Repairing these mutations would significantly improve the quality of life for patients with hereditary diseases. However, current procedures for repairing deleterious single-n...

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Detalles Bibliográficos
Autores principales: Yokouchi, Yuji, Suzuki, Shinichi, Ohtsuki, Noriko, Yamamoto, Kei, Noguchi, Satomi, Soejima, Yumi, Goto, Mizuki, Ishioka, Ken, Nakamura, Izumi, Suzuki, Satoru, Takenoshita, Seiichi, Era, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435196/
https://www.ncbi.nlm.nih.gov/pubmed/32811847
http://dx.doi.org/10.1038/s41598-020-70401-7

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