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Selection of a Full Agonist Combinatorial Antibody that Rescues Leptin Deficiency In Vivo
Growth factor deficiency in adulthood constitutes a distinct clinical syndrome with significant morbidities including abnormal body composition, reduced energy, affective disturbances, dyslipidemia, and increased cardiovascular risk. Protein replacement therapies using recombinant proteins or enzyme...
Autores principales: | Tao, Pingdong, Kuang, Yuanyuan, Li, Yu, Li, Wenping, Gao, Zibei, Liu, Lili, Qiang, Min, Zha, Zhao, Fan, Kun, Ma, Peixiang, Friedman, Jeffrey M., Yang, Guang, Lerner, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435230/ https://www.ncbi.nlm.nih.gov/pubmed/32832353 http://dx.doi.org/10.1002/advs.202000818 |
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