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Input-Output Relationship of CA1 Pyramidal Neurons Reveals Intact Homeostatic Mechanisms in a Mouse Model of Fragile X Syndrome

Cellular hyperexcitability is a salient feature of fragile X syndrome animal models. The cellular basis of hyperexcitability and how it responds to changing activity states is not fully understood. Here, we show increased axon initial segment length in CA1 of the Fmr1(−/y) mouse hippocampus, with in...

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Detalles Bibliográficos
Autores principales:	Booker, Sam A., Simões de Oliveira, Laura, Anstey, Natasha J., Kozic, Zrinko, Dando, Owen R., Jackson, Adam D., Baxter, Paul S., Isom, Lori L., Sherman, Diane L., Hardingham, Giles E., Brophy, Peter J., Wyllie, David J.A., Kind, Peter C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435362/ https://www.ncbi.nlm.nih.gov/pubmed/32783927 http://dx.doi.org/10.1016/j.celrep.2020.107988

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