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Flexibility of Biodegradable Polymer Stents with Different Strut Geometries
Objective: Biodegradable stents (BDSs) represent a new technological development in the field of cardiovascular angioplasty; good flexibility helps stents pass through tortuous vessels during delivery and reduces the amount of damage caused to blood vessels. This study investigates the relationship...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435406/ https://www.ncbi.nlm.nih.gov/pubmed/32726957 http://dx.doi.org/10.3390/ma13153332 |
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author | Chen, Chong Xiong, Yan Li, Zhongyou Chen, Yu |
author_facet | Chen, Chong Xiong, Yan Li, Zhongyou Chen, Yu |
author_sort | Chen, Chong |
collection | PubMed |
description | Objective: Biodegradable stents (BDSs) represent a new technological development in the field of cardiovascular angioplasty; good flexibility helps stents pass through tortuous vessels during delivery and reduces the amount of damage caused to blood vessels. This study investigates the relationship between flexibility and the geometry of BDS struts. Methods: Four stent struts with different geometry (circular, triangular, hexagonal, and spline curved) and the same links were modeled to evaluate their flexibility via a three-point bending experimental method and a numerical method. Results: The bending state of the four stents was well-balanced. The bending effect of the four stents was different. Under the same conditions, the circular and spline curved stents showed the best bending effects while the hexagonal stent was the worst. However, these differences were not significant. Conclusion: The flexibility of BDSs is related to the geometry of the struts and links; however, the geometry of the struts has less effect on flexibility than the links. The greater the area enclosed by the strut centerline, the better flexibility of the stent. |
format | Online Article Text |
id | pubmed-7435406 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-74354062020-08-28 Flexibility of Biodegradable Polymer Stents with Different Strut Geometries Chen, Chong Xiong, Yan Li, Zhongyou Chen, Yu Materials (Basel) Article Objective: Biodegradable stents (BDSs) represent a new technological development in the field of cardiovascular angioplasty; good flexibility helps stents pass through tortuous vessels during delivery and reduces the amount of damage caused to blood vessels. This study investigates the relationship between flexibility and the geometry of BDS struts. Methods: Four stent struts with different geometry (circular, triangular, hexagonal, and spline curved) and the same links were modeled to evaluate their flexibility via a three-point bending experimental method and a numerical method. Results: The bending state of the four stents was well-balanced. The bending effect of the four stents was different. Under the same conditions, the circular and spline curved stents showed the best bending effects while the hexagonal stent was the worst. However, these differences were not significant. Conclusion: The flexibility of BDSs is related to the geometry of the struts and links; however, the geometry of the struts has less effect on flexibility than the links. The greater the area enclosed by the strut centerline, the better flexibility of the stent. MDPI 2020-07-27 /pmc/articles/PMC7435406/ /pubmed/32726957 http://dx.doi.org/10.3390/ma13153332 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chen, Chong Xiong, Yan Li, Zhongyou Chen, Yu Flexibility of Biodegradable Polymer Stents with Different Strut Geometries |
title | Flexibility of Biodegradable Polymer Stents with Different Strut Geometries |
title_full | Flexibility of Biodegradable Polymer Stents with Different Strut Geometries |
title_fullStr | Flexibility of Biodegradable Polymer Stents with Different Strut Geometries |
title_full_unstemmed | Flexibility of Biodegradable Polymer Stents with Different Strut Geometries |
title_short | Flexibility of Biodegradable Polymer Stents with Different Strut Geometries |
title_sort | flexibility of biodegradable polymer stents with different strut geometries |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435406/ https://www.ncbi.nlm.nih.gov/pubmed/32726957 http://dx.doi.org/10.3390/ma13153332 |
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