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Flexibility of Biodegradable Polymer Stents with Different Strut Geometries

Objective: Biodegradable stents (BDSs) represent a new technological development in the field of cardiovascular angioplasty; good flexibility helps stents pass through tortuous vessels during delivery and reduces the amount of damage caused to blood vessels. This study investigates the relationship...

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Detalles Bibliográficos
Autores principales: Chen, Chong, Xiong, Yan, Li, Zhongyou, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435406/
https://www.ncbi.nlm.nih.gov/pubmed/32726957
http://dx.doi.org/10.3390/ma13153332
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author Chen, Chong
Xiong, Yan
Li, Zhongyou
Chen, Yu
author_facet Chen, Chong
Xiong, Yan
Li, Zhongyou
Chen, Yu
author_sort Chen, Chong
collection PubMed
description Objective: Biodegradable stents (BDSs) represent a new technological development in the field of cardiovascular angioplasty; good flexibility helps stents pass through tortuous vessels during delivery and reduces the amount of damage caused to blood vessels. This study investigates the relationship between flexibility and the geometry of BDS struts. Methods: Four stent struts with different geometry (circular, triangular, hexagonal, and spline curved) and the same links were modeled to evaluate their flexibility via a three-point bending experimental method and a numerical method. Results: The bending state of the four stents was well-balanced. The bending effect of the four stents was different. Under the same conditions, the circular and spline curved stents showed the best bending effects while the hexagonal stent was the worst. However, these differences were not significant. Conclusion: The flexibility of BDSs is related to the geometry of the struts and links; however, the geometry of the struts has less effect on flexibility than the links. The greater the area enclosed by the strut centerline, the better flexibility of the stent.
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spelling pubmed-74354062020-08-28 Flexibility of Biodegradable Polymer Stents with Different Strut Geometries Chen, Chong Xiong, Yan Li, Zhongyou Chen, Yu Materials (Basel) Article Objective: Biodegradable stents (BDSs) represent a new technological development in the field of cardiovascular angioplasty; good flexibility helps stents pass through tortuous vessels during delivery and reduces the amount of damage caused to blood vessels. This study investigates the relationship between flexibility and the geometry of BDS struts. Methods: Four stent struts with different geometry (circular, triangular, hexagonal, and spline curved) and the same links were modeled to evaluate their flexibility via a three-point bending experimental method and a numerical method. Results: The bending state of the four stents was well-balanced. The bending effect of the four stents was different. Under the same conditions, the circular and spline curved stents showed the best bending effects while the hexagonal stent was the worst. However, these differences were not significant. Conclusion: The flexibility of BDSs is related to the geometry of the struts and links; however, the geometry of the struts has less effect on flexibility than the links. The greater the area enclosed by the strut centerline, the better flexibility of the stent. MDPI 2020-07-27 /pmc/articles/PMC7435406/ /pubmed/32726957 http://dx.doi.org/10.3390/ma13153332 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chen, Chong
Xiong, Yan
Li, Zhongyou
Chen, Yu
Flexibility of Biodegradable Polymer Stents with Different Strut Geometries
title Flexibility of Biodegradable Polymer Stents with Different Strut Geometries
title_full Flexibility of Biodegradable Polymer Stents with Different Strut Geometries
title_fullStr Flexibility of Biodegradable Polymer Stents with Different Strut Geometries
title_full_unstemmed Flexibility of Biodegradable Polymer Stents with Different Strut Geometries
title_short Flexibility of Biodegradable Polymer Stents with Different Strut Geometries
title_sort flexibility of biodegradable polymer stents with different strut geometries
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435406/
https://www.ncbi.nlm.nih.gov/pubmed/32726957
http://dx.doi.org/10.3390/ma13153332
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