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Synergistic Effect of a Pleuromutilin Derivative with Tetracycline against Streptococcus suis In Vitro and in the Neutropenic Thigh Infection Model

Tetracycline (TET) has been widely used in the treatment of Streptococcus suis (S. suis) infection. However, it was found that the efficacy of many antibiotics in S. suis decreased significantly, especially tetracycline. In this study, GML-12 (a novel pleuromutilin derivative) was used in combinatio...

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Detalles Bibliográficos
Autores principales:	Chen, Fang, Wei, Meng-Chao, Luo, Yi-Dan, Jin, Zhen, Tang, You-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435606/ https://www.ncbi.nlm.nih.gov/pubmed/32752180 http://dx.doi.org/10.3390/molecules25153522

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