Oral Bioavailability Evaluation of Celastrol-Encapsulated Silk Fibroin Nanoparticles Using an Optimized LC-MS/MS Method

Celastrol (CL), a compound isolated from Tripterygium wilfordii, possesses various bioactivities such as antitumor, anti-inflammatory and anti-obesity effects. In previous studies, we developed CL-encapsulated silk fibroin nanoparticles (CL-SFNP) with satisfactory formulation properties and in vitro...

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Detalles Bibliográficos
Autores principales: Zhan, Shuyu, Paik, Amy, Onyeabor, Felicia, Ding, Baoyue, Prabhu, Sunil, Wang, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435660/
https://www.ncbi.nlm.nih.gov/pubmed/32731529
http://dx.doi.org/10.3390/molecules25153422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435660/
https://www.ncbi.nlm.nih.gov/pubmed/32731529
http://dx.doi.org/10.3390/molecules25153422

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