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Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death

Interferon-inducible guanylate-binding proteins (GBPs) promote cell-intrinsic defense through host cell death. GBPs target pathogens and pathogen-containing vacuoles and promote membrane disruption for release of microbial molecules that activate inflammasomes. GBP1 mediates pyroptosis or atypical a...

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Detalles Bibliográficos
Autores principales:	Fisch, Daniel, Clough, Barbara, Domart, Marie-Charlotte, Encheva, Vesela, Bando, Hironori, Snijders, Ambrosius P., Collinson, Lucy M., Yamamoto, Masahiro, Shenoy, Avinash R., Frickel, Eva-Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435695/ https://www.ncbi.nlm.nih.gov/pubmed/32783936 http://dx.doi.org/10.1016/j.celrep.2020.108008

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