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Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives

Coumarin derivatives are a class of compounds with a pronounced wide range of applications, especially in biological activities, in the medicine, pharmacology, cosmetics, coatings and food industry. Their potential applications are highly dependent on the nature of the substituents attached to their...

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Autores principales: Seoane-Rivero, Rubén, Ruiz-Bilbao, Estibaliz, Navarro, Rodrigo, Laza, José Manuel, Cuevas, José María, Artetxe, Beñat, Gutiérrez-Zorrilla, Juan M., Vilas-Vilela, José Luis, Marcos-Fernandez, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436329/
https://www.ncbi.nlm.nih.gov/pubmed/32751979
http://dx.doi.org/10.3390/molecules25153497
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author Seoane-Rivero, Rubén
Ruiz-Bilbao, Estibaliz
Navarro, Rodrigo
Laza, José Manuel
Cuevas, José María
Artetxe, Beñat
Gutiérrez-Zorrilla, Juan M.
Vilas-Vilela, José Luis
Marcos-Fernandez, Ángel
author_facet Seoane-Rivero, Rubén
Ruiz-Bilbao, Estibaliz
Navarro, Rodrigo
Laza, José Manuel
Cuevas, José María
Artetxe, Beñat
Gutiérrez-Zorrilla, Juan M.
Vilas-Vilela, José Luis
Marcos-Fernandez, Ángel
author_sort Seoane-Rivero, Rubén
collection PubMed
description Coumarin derivatives are a class of compounds with a pronounced wide range of applications, especially in biological activities, in the medicine, pharmacology, cosmetics, coatings and food industry. Their potential applications are highly dependent on the nature of the substituents attached to their nucleus. These substituents modulate their photochemical and photophysical properties, as well as their interactions in their crystalline form, which largely determines the final field of application. Therefore, in this work a series of mono and dihydroxylated coumarin derivatives with different chemical substituents were synthesized and characterized by UV-Visible spectroscopy, thermal analysis (differential scanning calorimetry (DSC) and TGA), (1)H NMR and X-Ray Diffraction to identify limitations and possibilities as a function of the molecular structure for expanding their applications in polymer science.
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spelling pubmed-74363292020-08-24 Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives Seoane-Rivero, Rubén Ruiz-Bilbao, Estibaliz Navarro, Rodrigo Laza, José Manuel Cuevas, José María Artetxe, Beñat Gutiérrez-Zorrilla, Juan M. Vilas-Vilela, José Luis Marcos-Fernandez, Ángel Molecules Article Coumarin derivatives are a class of compounds with a pronounced wide range of applications, especially in biological activities, in the medicine, pharmacology, cosmetics, coatings and food industry. Their potential applications are highly dependent on the nature of the substituents attached to their nucleus. These substituents modulate their photochemical and photophysical properties, as well as their interactions in their crystalline form, which largely determines the final field of application. Therefore, in this work a series of mono and dihydroxylated coumarin derivatives with different chemical substituents were synthesized and characterized by UV-Visible spectroscopy, thermal analysis (differential scanning calorimetry (DSC) and TGA), (1)H NMR and X-Ray Diffraction to identify limitations and possibilities as a function of the molecular structure for expanding their applications in polymer science. MDPI 2020-07-31 /pmc/articles/PMC7436329/ /pubmed/32751979 http://dx.doi.org/10.3390/molecules25153497 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Seoane-Rivero, Rubén
Ruiz-Bilbao, Estibaliz
Navarro, Rodrigo
Laza, José Manuel
Cuevas, José María
Artetxe, Beñat
Gutiérrez-Zorrilla, Juan M.
Vilas-Vilela, José Luis
Marcos-Fernandez, Ángel
Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives
title Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives
title_full Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives
title_fullStr Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives
title_full_unstemmed Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives
title_short Structural Characterization of Mono and Dihydroxylated Umbelliferone Derivatives
title_sort structural characterization of mono and dihydroxylated umbelliferone derivatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436329/
https://www.ncbi.nlm.nih.gov/pubmed/32751979
http://dx.doi.org/10.3390/molecules25153497
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