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Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring

AIM: To describe the effect of the stringent lockdown measures, introduced in the UK on 23 March 2020 to curtail the transmission of COVID‐19, on glycaemic control in people with type 1 diabetes using flash glucose monitoring. METHODS: We undertook an observational study of 572 individuals with type...

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Autores principales: Dover, A. R., Ritchie, S. A., McKnight, J. A., Strachan, M. W. J., Zammitt, N. N., Wake, D.J., Forbes, S., Stimson, R. H., Gibb, F. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436620/
https://www.ncbi.nlm.nih.gov/pubmed/32740984
http://dx.doi.org/10.1111/dme.14374
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author Dover, A. R.
Ritchie, S. A.
McKnight, J. A.
Strachan, M. W. J.
Zammitt, N. N.
Wake, D.J.
Forbes, S.
Stimson, R. H.
Gibb, F. W.
author_facet Dover, A. R.
Ritchie, S. A.
McKnight, J. A.
Strachan, M. W. J.
Zammitt, N. N.
Wake, D.J.
Forbes, S.
Stimson, R. H.
Gibb, F. W.
author_sort Dover, A. R.
collection PubMed
description AIM: To describe the effect of the stringent lockdown measures, introduced in the UK on 23 March 2020 to curtail the transmission of COVID‐19, on glycaemic control in people with type 1 diabetes using flash glucose monitoring. METHODS: We undertook an observational study of 572 individuals with type 1 diabetes for whom paired flash glucose monitoring data were available between early March and May 2020. The primary outcome was change in flash glucose monitoring variables. We also assessed clinical variables associated with change in glycaemic control. RESULTS: Percentage of time in range increased between March and May 2020 [median (interquartile range) 53 (41–64)% vs 56 (45–68)%; P < 0.001], with associated improvements in standard deviation of glucose (P <0.001) and estimated HbA(1c) (P <0.001). There was a small reduction in the number of individuals meeting the hypoglycaemia target of <5% per day (64% vs 58%; P = 0.004). Comparing changes in flash glucose monitoring data from March to May in 2019 with the same period in 2020 confirmed that these differences were confined to 2020. Socio‐economic deprivation was an independent predictor of a ≥5% reduction in time in range during lockdown (odds ratio 0.45 for people in the two most affluent Scottish Index of Multiple Deprivation quintiles; P <0.001). CONCLUSIONS: Lockdown was not associated with a significant deterioration in glycaemic control in people with type 1 diabetes using flash glucose monitoring. However, socio‐economic deprivation appeared to increase the risk of decline in glycaemic control, which has implications for how support is focused in challenging times.
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spelling pubmed-74366202020-08-19 Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring Dover, A. R. Ritchie, S. A. McKnight, J. A. Strachan, M. W. J. Zammitt, N. N. Wake, D.J. Forbes, S. Stimson, R. H. Gibb, F. W. Diabet Med Research: Care Delivery AIM: To describe the effect of the stringent lockdown measures, introduced in the UK on 23 March 2020 to curtail the transmission of COVID‐19, on glycaemic control in people with type 1 diabetes using flash glucose monitoring. METHODS: We undertook an observational study of 572 individuals with type 1 diabetes for whom paired flash glucose monitoring data were available between early March and May 2020. The primary outcome was change in flash glucose monitoring variables. We also assessed clinical variables associated with change in glycaemic control. RESULTS: Percentage of time in range increased between March and May 2020 [median (interquartile range) 53 (41–64)% vs 56 (45–68)%; P < 0.001], with associated improvements in standard deviation of glucose (P <0.001) and estimated HbA(1c) (P <0.001). There was a small reduction in the number of individuals meeting the hypoglycaemia target of <5% per day (64% vs 58%; P = 0.004). Comparing changes in flash glucose monitoring data from March to May in 2019 with the same period in 2020 confirmed that these differences were confined to 2020. Socio‐economic deprivation was an independent predictor of a ≥5% reduction in time in range during lockdown (odds ratio 0.45 for people in the two most affluent Scottish Index of Multiple Deprivation quintiles; P <0.001). CONCLUSIONS: Lockdown was not associated with a significant deterioration in glycaemic control in people with type 1 diabetes using flash glucose monitoring. However, socio‐economic deprivation appeared to increase the risk of decline in glycaemic control, which has implications for how support is focused in challenging times. John Wiley and Sons Inc. 2020-09-28 2021-01 /pmc/articles/PMC7436620/ /pubmed/32740984 http://dx.doi.org/10.1111/dme.14374 Text en © 2020 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research: Care Delivery
Dover, A. R.
Ritchie, S. A.
McKnight, J. A.
Strachan, M. W. J.
Zammitt, N. N.
Wake, D.J.
Forbes, S.
Stimson, R. H.
Gibb, F. W.
Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring
title Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring
title_full Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring
title_fullStr Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring
title_full_unstemmed Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring
title_short Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring
title_sort assessment of the effect of the covid‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring
topic Research: Care Delivery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436620/
https://www.ncbi.nlm.nih.gov/pubmed/32740984
http://dx.doi.org/10.1111/dme.14374
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