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Outcome of COVID‐19 in multiple myeloma patients in relation to treatment
COVID‐19 has emerged as a global pandemic. Cancer patients have been reported to be at higher risk for adverse outcome of COVID‐19. Studies are ongoing to decipher the risk factors and risk groups among cancer patients as well as strategies to refine treatment approaches. Here, we report eight patie...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436812/ https://www.ncbi.nlm.nih.gov/pubmed/32745304 http://dx.doi.org/10.1111/ejh.13502 |
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author | Susek, Katharina Helene Gran, Charlotte Ljunggren, Hans‐Gustaf Alici, Evren Nahi, Hareth |
author_facet | Susek, Katharina Helene Gran, Charlotte Ljunggren, Hans‐Gustaf Alici, Evren Nahi, Hareth |
author_sort | Susek, Katharina Helene |
collection | PubMed |
description | COVID‐19 has emerged as a global pandemic. Cancer patients have been reported to be at higher risk for adverse outcome of COVID‐19. Studies are ongoing to decipher the risk factors and risk groups among cancer patients as well as strategies to refine treatment approaches. Here, we report eight patients with multiple myeloma that underwent immunomodulatory therapies with daratumumab or lenalidomide‐based combination treatments and one patient with smoldering multiple myeloma, all of which presented with symptomatic COVID‐19. We report that patients that succumbed to COVID‐19 presented with either progressive tumor disease under daratumumab treatment or were in remission under lenalidomide‐dexamethasone treatment. |
format | Online Article Text |
id | pubmed-7436812 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74368122020-08-19 Outcome of COVID‐19 in multiple myeloma patients in relation to treatment Susek, Katharina Helene Gran, Charlotte Ljunggren, Hans‐Gustaf Alici, Evren Nahi, Hareth Eur J Haematol Original Articles COVID‐19 has emerged as a global pandemic. Cancer patients have been reported to be at higher risk for adverse outcome of COVID‐19. Studies are ongoing to decipher the risk factors and risk groups among cancer patients as well as strategies to refine treatment approaches. Here, we report eight patients with multiple myeloma that underwent immunomodulatory therapies with daratumumab or lenalidomide‐based combination treatments and one patient with smoldering multiple myeloma, all of which presented with symptomatic COVID‐19. We report that patients that succumbed to COVID‐19 presented with either progressive tumor disease under daratumumab treatment or were in remission under lenalidomide‐dexamethasone treatment. John Wiley and Sons Inc. 2020-08-18 2020-12 /pmc/articles/PMC7436812/ /pubmed/32745304 http://dx.doi.org/10.1111/ejh.13502 Text en © 2020 The Authors. European Journal of Haematology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Susek, Katharina Helene Gran, Charlotte Ljunggren, Hans‐Gustaf Alici, Evren Nahi, Hareth Outcome of COVID‐19 in multiple myeloma patients in relation to treatment |
title | Outcome of COVID‐19 in multiple myeloma patients in relation to treatment |
title_full | Outcome of COVID‐19 in multiple myeloma patients in relation to treatment |
title_fullStr | Outcome of COVID‐19 in multiple myeloma patients in relation to treatment |
title_full_unstemmed | Outcome of COVID‐19 in multiple myeloma patients in relation to treatment |
title_short | Outcome of COVID‐19 in multiple myeloma patients in relation to treatment |
title_sort | outcome of covid‐19 in multiple myeloma patients in relation to treatment |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436812/ https://www.ncbi.nlm.nih.gov/pubmed/32745304 http://dx.doi.org/10.1111/ejh.13502 |
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