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Outcome of COVID‐19 in multiple myeloma patients in relation to treatment

COVID‐19 has emerged as a global pandemic. Cancer patients have been reported to be at higher risk for adverse outcome of COVID‐19. Studies are ongoing to decipher the risk factors and risk groups among cancer patients as well as strategies to refine treatment approaches. Here, we report eight patie...

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Autores principales: Susek, Katharina Helene, Gran, Charlotte, Ljunggren, Hans‐Gustaf, Alici, Evren, Nahi, Hareth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436812/
https://www.ncbi.nlm.nih.gov/pubmed/32745304
http://dx.doi.org/10.1111/ejh.13502
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author Susek, Katharina Helene
Gran, Charlotte
Ljunggren, Hans‐Gustaf
Alici, Evren
Nahi, Hareth
author_facet Susek, Katharina Helene
Gran, Charlotte
Ljunggren, Hans‐Gustaf
Alici, Evren
Nahi, Hareth
author_sort Susek, Katharina Helene
collection PubMed
description COVID‐19 has emerged as a global pandemic. Cancer patients have been reported to be at higher risk for adverse outcome of COVID‐19. Studies are ongoing to decipher the risk factors and risk groups among cancer patients as well as strategies to refine treatment approaches. Here, we report eight patients with multiple myeloma that underwent immunomodulatory therapies with daratumumab or lenalidomide‐based combination treatments and one patient with smoldering multiple myeloma, all of which presented with symptomatic COVID‐19. We report that patients that succumbed to COVID‐19 presented with either progressive tumor disease under daratumumab treatment or were in remission under lenalidomide‐dexamethasone treatment.
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spelling pubmed-74368122020-08-19 Outcome of COVID‐19 in multiple myeloma patients in relation to treatment Susek, Katharina Helene Gran, Charlotte Ljunggren, Hans‐Gustaf Alici, Evren Nahi, Hareth Eur J Haematol Original Articles COVID‐19 has emerged as a global pandemic. Cancer patients have been reported to be at higher risk for adverse outcome of COVID‐19. Studies are ongoing to decipher the risk factors and risk groups among cancer patients as well as strategies to refine treatment approaches. Here, we report eight patients with multiple myeloma that underwent immunomodulatory therapies with daratumumab or lenalidomide‐based combination treatments and one patient with smoldering multiple myeloma, all of which presented with symptomatic COVID‐19. We report that patients that succumbed to COVID‐19 presented with either progressive tumor disease under daratumumab treatment or were in remission under lenalidomide‐dexamethasone treatment. John Wiley and Sons Inc. 2020-08-18 2020-12 /pmc/articles/PMC7436812/ /pubmed/32745304 http://dx.doi.org/10.1111/ejh.13502 Text en © 2020 The Authors. European Journal of Haematology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Susek, Katharina Helene
Gran, Charlotte
Ljunggren, Hans‐Gustaf
Alici, Evren
Nahi, Hareth
Outcome of COVID‐19 in multiple myeloma patients in relation to treatment
title Outcome of COVID‐19 in multiple myeloma patients in relation to treatment
title_full Outcome of COVID‐19 in multiple myeloma patients in relation to treatment
title_fullStr Outcome of COVID‐19 in multiple myeloma patients in relation to treatment
title_full_unstemmed Outcome of COVID‐19 in multiple myeloma patients in relation to treatment
title_short Outcome of COVID‐19 in multiple myeloma patients in relation to treatment
title_sort outcome of covid‐19 in multiple myeloma patients in relation to treatment
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436812/
https://www.ncbi.nlm.nih.gov/pubmed/32745304
http://dx.doi.org/10.1111/ejh.13502
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