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Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress

Dysbiosis of gut microbiota is strongly associated with metabolic diseases including diabetes mellitus, obesity, and cardiovascular disease. Recent studies indicate that Trimethylamine N-oxide (TMAO), a gut microbe-dependent metabolite is implicated in the development of age-related cognitive declin...

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Detalles Bibliográficos
Autores principales:	Govindarajulu, Manoj, Pinky, Priyanka D., Steinke, Ian, Bloemer, Jenna, Ramesh, Sindhu, Kariharan, Thiruchelvan, Rella, Robert T., Bhattacharya, Subhrajit, Dhanasekaran, Muralikrishnan, Suppiramaniam, Vishnu, Amin, Rajesh H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437142/ https://www.ncbi.nlm.nih.gov/pubmed/32903435 http://dx.doi.org/10.3389/fnmol.2020.00138

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