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Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis

Myeloid cells contribute to inflammation and demyelination in the early stages of multiple sclerosis (MS), but it is still unclear to what extent these cells are involved in active lesion formation in progressive MS (PMS). Here, we have harnessed the power of single-cell mass cytometry (CyTOF) to co...

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Detalles Bibliográficos
Autores principales: Böttcher, Chotima, van der Poel, Marlijn, Fernández-Zapata, Camila, Schlickeiser, Stephan, Leman, Julia K. H., Hsiao, Cheng-Chih, Mizee, Mark R., Adelia, Vincenten, Maria C. J., Kunkel, Desiree, Huitinga, Inge, Hamann, Jörg, Priller, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437178/
https://www.ncbi.nlm.nih.gov/pubmed/32811567
http://dx.doi.org/10.1186/s40478-020-01010-8