Gene Therapy with MiRNA-Mediated Targeting of Mcl-1 Promotes the Sensitivity of Non-Small Cell Lung Cancer Cells to Treatment with ABT-737

BACKGROUND: Despite the dramatic efficacy of ABT-737, a large percentage of cancer cells ultimately become resistance to this drug. Evidences show that over-expression of Mcl-1 is linked to ABT-737 resistance in NSCLC cells. The aim of this study was to investigate the effect of miRNA-101 on Mcl-1 e...

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Detalles Bibliográficos
Autores principales: Shahverdi, Mahshid, Amini, Razieh, Amri, Jamal, Karami, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437340/
https://www.ncbi.nlm.nih.gov/pubmed/32212793
http://dx.doi.org/10.31557/APJCP.2020.21.3.675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437340/
https://www.ncbi.nlm.nih.gov/pubmed/32212793
http://dx.doi.org/10.31557/APJCP.2020.21.3.675

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