ATM and P53 differentially regulate pancreatic beta cell survival in Ins1E cells

Pancreatic beta cell death is a hallmark of type 1 and 2 diabetes (T1D/T2D), but the underlying molecular mechanisms are incompletely understood. Key proteins of the DNA damage response (DDR), including tumor protein P53 (P53, also known as TP53 or TRP53 in rodents) and Ataxia Telangiectasia Mutated...

Descripción completa

Detalles Bibliográficos
Autores principales: Uhlemeyer, Celina, Müller, Nadine, Grieß, Kerstin, Wessel, Corinna, Schlegel, Caroline, Kuboth, Jennifer, Belgardt, Bengt-Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437460/
https://www.ncbi.nlm.nih.gov/pubmed/32810137
http://dx.doi.org/10.1371/journal.pone.0237669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437460/
https://www.ncbi.nlm.nih.gov/pubmed/32810137
http://dx.doi.org/10.1371/journal.pone.0237669

Ejemplares similares