P53 in the impaired lungs

Our laboratory is focused on investigating the supportive role of P53 towards the maintenance of lung homeostasis. Acute lung injury, acute respiratory distress syndrome, chronic obstructive pulmonary disease, pulmonary fibrosis, bronchial asthma, pulmonary arterial hypertension, pneumonia and tuber...

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Detalles Bibliográficos
Autores principales: Uddin, Mohammad A., Barabutis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437512/
https://www.ncbi.nlm.nih.gov/pubmed/32846356
http://dx.doi.org/10.1016/j.dnarep.2020.102952
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author Uddin, Mohammad A.
Barabutis, Nektarios
author_facet Uddin, Mohammad A.
Barabutis, Nektarios
author_sort Uddin, Mohammad A.
collection PubMed
description Our laboratory is focused on investigating the supportive role of P53 towards the maintenance of lung homeostasis. Acute lung injury, acute respiratory distress syndrome, chronic obstructive pulmonary disease, pulmonary fibrosis, bronchial asthma, pulmonary arterial hypertension, pneumonia and tuberculosis are respiratory pathologies, associated with dysfunctions of this endothelium defender (P53). Herein we review the evolving role of P53 towards the aforementioned inflammatory disorders, to potentially reveal new therapeutic possibilities in pulmonary disease.
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spelling pubmed-74375122020-08-20 P53 in the impaired lungs Uddin, Mohammad A. Barabutis, Nektarios DNA Repair (Amst) Review Article Our laboratory is focused on investigating the supportive role of P53 towards the maintenance of lung homeostasis. Acute lung injury, acute respiratory distress syndrome, chronic obstructive pulmonary disease, pulmonary fibrosis, bronchial asthma, pulmonary arterial hypertension, pneumonia and tuberculosis are respiratory pathologies, associated with dysfunctions of this endothelium defender (P53). Herein we review the evolving role of P53 towards the aforementioned inflammatory disorders, to potentially reveal new therapeutic possibilities in pulmonary disease. Elsevier B.V. 2020-11 2020-08-19 /pmc/articles/PMC7437512/ /pubmed/32846356 http://dx.doi.org/10.1016/j.dnarep.2020.102952 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
Uddin, Mohammad A.
Barabutis, Nektarios
P53 in the impaired lungs
title P53 in the impaired lungs
title_full P53 in the impaired lungs
title_fullStr P53 in the impaired lungs
title_full_unstemmed P53 in the impaired lungs
title_short P53 in the impaired lungs
title_sort p53 in the impaired lungs
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437512/
https://www.ncbi.nlm.nih.gov/pubmed/32846356
http://dx.doi.org/10.1016/j.dnarep.2020.102952
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