First insight into the whole-genome sequence variations in Mycobacterium bovis BCG-1 (Russia) vaccine seed lots and their progeny clinical isolates from children with BCG-induced adverse events

BACKGROUND: The only licensed live Bacille Calmette-Guérin (BCG) vaccine used to prevent severe childhood tuberculosis comprises genetically divergent strains with variable protective efficacy and rates of BCG-induced adverse events. The whole-genome sequencing (WGS) allowed evaluating the genome st...

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Detalles Bibliográficos
Autores principales: Narvskaya, Olga, Starkova, Daria, Levi, Diana, Alexandrova, Natalia, Molchanov, Vladimir, Chernyaeva, Ekaterina, Vyazovaya, Anna, Mushkin, Alexander, Zhuravlev, Viacheslav, Solovieva, Natalia, Vishnevskiy, Boris, Mokrousov, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437937/
https://www.ncbi.nlm.nih.gov/pubmed/32811436
http://dx.doi.org/10.1186/s12864-020-06973-5

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