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Transport and fate of human expiratory droplets—A modeling approach

The transport and fate of human expiratory droplets play a key role in the transmission of respiratory infectious diseases. In this paper, we present a modeling approach to understand the fundamental dynamics of exhaled droplets in human respiratory activities. The model solves a series of governing...

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Detalles Bibliográficos
Autores principales: Wang, Binbin, Wu, Huijie, Wan, Xiu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437951/
https://www.ncbi.nlm.nih.gov/pubmed/32831538
http://dx.doi.org/10.1063/5.0021280
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author Wang, Binbin
Wu, Huijie
Wan, Xiu-Feng
author_facet Wang, Binbin
Wu, Huijie
Wan, Xiu-Feng
author_sort Wang, Binbin
collection PubMed
description The transport and fate of human expiratory droplets play a key role in the transmission of respiratory infectious diseases. In this paper, we present a modeling approach to understand the fundamental dynamics of exhaled droplets in human respiratory activities. The model solves a series of governing equations of droplets and uses a continuous random walk model to simulate turbulent fluctuations in violent expiratory events. The validation of the model shows the improvement in the prediction of dispersion of median-sized droplets. We show that these droplets are sensitive to environmental conditions, including temperature, humidity, and ambient flows. Applying the model to a set of idealized conditions such as free-fall and continuous jets, we demonstrate significantly different impacts of environmental parameters on droplets with different sizes. Using a realistic droplet size distribution and cough duration, we quantify the transport and fate of droplets in the near field of source and the potential influences by ambient conditions. The model we developed from this study could be applied to study the mechanisms for airborne pathogens, e.g., influenza virus and new coronavirus.
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spelling pubmed-74379512020-08-19 Transport and fate of human expiratory droplets—A modeling approach Wang, Binbin Wu, Huijie Wan, Xiu-Feng Phys Fluids (1994) ARTICLES The transport and fate of human expiratory droplets play a key role in the transmission of respiratory infectious diseases. In this paper, we present a modeling approach to understand the fundamental dynamics of exhaled droplets in human respiratory activities. The model solves a series of governing equations of droplets and uses a continuous random walk model to simulate turbulent fluctuations in violent expiratory events. The validation of the model shows the improvement in the prediction of dispersion of median-sized droplets. We show that these droplets are sensitive to environmental conditions, including temperature, humidity, and ambient flows. Applying the model to a set of idealized conditions such as free-fall and continuous jets, we demonstrate significantly different impacts of environmental parameters on droplets with different sizes. Using a realistic droplet size distribution and cough duration, we quantify the transport and fate of droplets in the near field of source and the potential influences by ambient conditions. The model we developed from this study could be applied to study the mechanisms for airborne pathogens, e.g., influenza virus and new coronavirus. AIP Publishing LLC 2020-08-01 /pmc/articles/PMC7437951/ /pubmed/32831538 http://dx.doi.org/10.1063/5.0021280 Text en Copyright © 2020 Author(s) Published under license by AIP Publishing. 1070-6631/2020/32(8)/083307/13/$30.00 All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).
spellingShingle ARTICLES
Wang, Binbin
Wu, Huijie
Wan, Xiu-Feng
Transport and fate of human expiratory droplets—A modeling approach
title Transport and fate of human expiratory droplets—A modeling approach
title_full Transport and fate of human expiratory droplets—A modeling approach
title_fullStr Transport and fate of human expiratory droplets—A modeling approach
title_full_unstemmed Transport and fate of human expiratory droplets—A modeling approach
title_short Transport and fate of human expiratory droplets—A modeling approach
title_sort transport and fate of human expiratory droplets—a modeling approach
topic ARTICLES
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437951/
https://www.ncbi.nlm.nih.gov/pubmed/32831538
http://dx.doi.org/10.1063/5.0021280
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