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Interplay of m(6)A and H3K27 trimethylation restrains inflammation during bacterial infection

While N(6)-methyladenosine (m(6)A) is the most prevalent modification of eukaryotic messenger RNA (mRNA) involved in various cellular responses, its role in modulating bacteria-induced inflammatory response remains elusive. Here, we showed that loss of the m(6)A reader YTH-domain family 2 (YTHDF2) p...

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Detalles Bibliográficos
Autores principales: Wu, Chenglei, Chen, Weixin, He, Jincan, Jin, Shouheng, Liu, Yukun, Yi, Yang, Gao, Zhuoxing, Yang, Jiayan, Yang, Jianhua, Cui, Jun, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438091/
https://www.ncbi.nlm.nih.gov/pubmed/32875102
http://dx.doi.org/10.1126/sciadv.aba0647