Repeat radiation with bevacizumab and minocycline in bevacizumab-refractory high grade gliomas: a prospective phase 1 trial

INTRODUCTION: There are no effective treatments for gliomas after progression on radiation, temozolomide, and bevacizumab. Microglia activation may be involved in radiation resistance and can be inhibited by the brain penetrating antibiotic minocycline. In this phase 1 trial, we examined the safety...

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Detalles Bibliográficos
Autores principales: Cohen, Adam L., Anker, Christopher J., Johnson, Brett, Burt, Lindsay M., Shrieve, Dennis C., Salzman, Karen, Jensen, Randy, Boucher, Ken, Colman, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438283/
https://www.ncbi.nlm.nih.gov/pubmed/32506371
http://dx.doi.org/10.1007/s11060-020-03551-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438283/
https://www.ncbi.nlm.nih.gov/pubmed/32506371
http://dx.doi.org/10.1007/s11060-020-03551-3

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