Cargando…

Emulsified silicone oil is taken up by and induces pro-inflammatory response in primary retinal microglia

PURPOSE: Silicone oil is used as endotamponade in combination with vitrectomy. Thinning of retinal layers and loss of retinal cells under silicone oil use have been found. Here, we investigate the influence of silicone oil on primary microglia cells. METHODS: Primary microglia cells were prepared fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klettner, Alexa, Harms, Antonia, Waetzig, Vicki, Tode, Jan, Purtskhvanidze, Konstantine, Roider, Johann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438289/ https://www.ncbi.nlm.nih.gov/pubmed/32500303 http://dx.doi.org/10.1007/s00417-020-04763-z

Ejemplares similares

Pro-inflammatory activation changes intracellular transport of bevacizumab in the retinal pigment epithelium in vitro
por: Hildebrandt, Julia, et al.
Publicado: (2021)

Basolateral activation with TLR agonists induces polarized cytokine release and reduces barrier function in RPE in vitro
por: Terheyden, Laura, et al.
Publicado: (2020)

Retinal Pigment Epithelium Expressed Toll-like Receptors and Their Potential Role in Age-Related Macular Degeneration
por: Klettner, Alexa, et al.
Publicado: (2021)

Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models
por: Tode, Jan, et al.
Publicado: (2019)

Open globe and penetrating eyelid injuries from fish hooks
por: Purtskhvanidze, Konstantine, et al.
Publicado: (2019)

Long-term results of glaucoma drainage device surgery
por: Purtskhvanidze, Konstantine, et al.
Publicado: (2019)

Interaction of High-Molecular Weight Fucoidan from Laminaria hyperborea with Natural Functions of the Retinal Pigment Epithelium
por: Dörschmann, Philipp, et al.
Publicado: (2023)

Anti-inflammatory properties of antiangiogenic fucoidan in retinal pigment epithelium cells
por: Dörschmann, Philipp, et al.
Publicado: (2023)

Thermal Stimulation of the Retina Reduces Bruch's Membrane Thickness in Age Related Macular Degeneration Mouse Models
por: Tode, Jan, et al.
Publicado: (2018)

Modulation of inflammatory processes by thermal stimulating and RPE regenerative laser therapies in age related macular degeneration mouse models
por: Richert, Elisabeth, et al.
Publicado: (2020)

Regulation of constitutive vascular endothelial growth factor secretion in retinal pigment epithelium/choroid organ cultures: p38, nuclear factor kappaB, and the vascular endothelial growth factor receptor-2/phosphatidylinositol 3 kinase pathway
por: Klettner, Alexa, et al.
Publicado: (2013)

(106)Ruthenium eye plaque brachytherapy in the management of medium sized uveal melanoma
por: Jiang, Ping, et al.
Publicado: (2020)

Fucoidan Reduces Secretion and Expression of Vascular Endothelial Growth Factor in the Retinal Pigment Epithelium and Reduces Angiogenesis In Vitro
por: Dithmer, Michaela, et al.
Publicado: (2014)

Effects of Sulfated Fucans from Laminaria hyperborea Regarding VEGF Secretion, Cell Viability, and Oxidative Stress and Correlation with Molecular Weight
por: Dörschmann, Philipp, et al.
Publicado: (2019)

Fundus autofluorescence abnormalities can predict fluorescein angiography abnormalities in patients with chronic central serous chorioretinopathy
por: Mohabati, Danial, et al.
Publicado: (2023)

The impact of axial length on retinal tamponade for gas, silicone oil, and heavy silicone oil, using an in vitro model
por: Hillier, Roxane J., et al.
Publicado: (2010)

Selective retina therapy and thermal stimulation of the retina: different regenerative properties - implications for AMD therapy
por: Richert, Elisabeth, et al.
Publicado: (2021)

Comparison of Fucoidans from Saccharina latissima Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium
por: Dörschmann, Philipp, et al.
Publicado: (2023)

Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study
por: von der Burchard, Claus, et al.
Publicado: (2022)

The Influence of Melatonin and Light on VEGF Secretion in Primary RPE Cells
por: Klettner, Alexa, et al.
Publicado: (2021)

Effects of Crude Fucus distichus Subspecies evanescens Fucoidan Extract on Retinal Pigment Epithelium Cells―Implications for Use in Age-Related Macular Degeneration
por: Rohwer, Kevin, et al.
Publicado: (2019)

Basal and apical regulation of VEGF-A and placenta growth factor in the RPE/choroid and primary RPE
por: Klettner, Alexa, et al.
Publicado: (2015)

Effects of Fucoidans from Five Different Brown Algae on Oxidative Stress and VEGF Interference in Ocular Cells
por: Dörschmann, Philipp, et al.
Publicado: (2019)

Effects of a Newly Developed Enzyme-Assisted Extraction Method on the Biological Activities of Fucoidans in Ocular Cells
por: Dörschmann, Philipp, et al.
Publicado: (2020)

Comparison of the Effects of Fucoidans on the Cell Viability of Tumor and Non-Tumor Cell Lines
por: Bittkau, Kaya Saskia, et al.
Publicado: (2019)

Myopic retinoschisis with intraretinal emulsified silicone oil appearing as a macular hyperoleon
por: Schouten, Ike M, et al.
Publicado: (2020)

Fucoidan Does Not Exert Anti-Tumorigenic Effects on Uveal Melanoma Cell Lines
por: Dithmer, Michaela, et al.
Publicado: (2017)

Evaluation of a Brown Seaweed Extract from Dictyosiphon foeniculaceus as a Potential Therapeutic Agent for the Treatment of Glioblastoma and Uveal Melanoma
por: Dörschmann, Philipp, et al.
Publicado: (2020)

Comparison of Repeated Fluid-Air Exchange and Passive Drainage for Removing Residual Emulsified Silicone Oil Droplets
por: Yu, Jian, et al.
Publicado: (2020)

Blocking TrkB’s Effectors Reveal Benefits of the Road Not Taken
por: Danzer, Steve C.
Publicado: (2019)

Baicalein—A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury
por: Pan, Li, et al.
Publicado: (2022)

Magnetic nanoparticles in primary neural cell cultures are mainly taken up by microglia
por: Pinkernelle, Josephine, et al.
Publicado: (2012)

Erratum to “Comparison of Repeated Fluid-Air Exchange and Passive Drainage for Removing Residual Emulsified Silicone Oil Droplets”
por: Yu, Jian, et al.
Publicado: (2020)

Evaluation of the Effects of Fucoidans from Fucus Species and Laminaria hyperborea against Oxidative Stress and Iron-Dependent Cell Death
por: Dörschmann, Philipp, et al.
Publicado: (2021)

Dual extra-retinal origins of microglia in the model of retinal microglia repopulation
por: Huang, Yubin, et al.
Publicado: (2018)

The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia
por: Cao, Shuwen, et al.
Publicado: (2012)

Selective Laser Trabeculoplasty for Glaucoma Secondary to Emulsified Silicone Oil after Pars Plana Vitrectomy: A Pilot Study
por: Alkin, Zeynep, et al.
Publicado: (2014)

Microglia in Retinal Degeneration
por: Rashid, Khalid, et al.
Publicado: (2019)

Migration of silicone oil for retinal detachment()
por: Allen, Claire, et al.
Publicado: (2022)

Fucoidan as a Potential Therapeutic for Major Blinding Diseases—A Hypothesis
por: Klettner, Alexa
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ieim3qlr9pjdnspdvl2h9c0hva