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High efavirenz levels but not neurofilament light plasma levels are associated with poor neurocognitive functioning in asymptomatic HIV patients

The aim of this study is to assess the effect of efavirenz exposure on neurocognitive functioning and investigate plasma neurofilament light (Nfl) as a biomarker for neurocognitive damage. Sub-analysis of the ESCAPE-study, a randomised controlled trial where virologically suppressed, cognitively asy...

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Detalles Bibliográficos
Autores principales: Hakkers, Charlotte S., Hermans, Anne Marie, van Maarseveen, Erik M., Teunissen, Charlotte E., Verberk, Inge M. W., Arends, Joop E., Hoepelman, Andy I. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438296/
https://www.ncbi.nlm.nih.gov/pubmed/32524424
http://dx.doi.org/10.1007/s13365-020-00860-1