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Tumour suppressor 15-hydroxyprostaglandin dehydrogenase induces differentiation in colon cancer via GLI1 inhibition

Inflammation is an established risk factor for colorectal cancer. We and others have shown that colorectal cancer patients with elevated cysteinyl leukotriene receptor 2 (CysLT(2)R) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) levels exhibit good prognoses. However, both CysLT(2)R and 15-PGDH...

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Detalles Bibliográficos
Autores principales:	Satapathy, Shakti Ranjan, Topi, Geriolda, Osman, Janina, Hellman, Karin, Ek, Fredrik, Olsson, Roger, Sime, Wondossen, Mehdawi, Lubna M., Sjölander, Anita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438320/ https://www.ncbi.nlm.nih.gov/pubmed/32814764 http://dx.doi.org/10.1038/s41389-020-00256-0

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