(99m)Tc-labeled nanocolloid drugs: development methods

The work considers the problem of obtaining nanocolloid radiopharmaceuticals (RPs) and studying their functional suitability for diagnosing sentinel lymph nodes (SLN) in cancer patients. Two principal approaches to the formation of technetium-99m-labeled particles based on inorganic and organic matr...

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Autores principales: Sadkin, Vladimir, Sкuridin, Viktor, Nesterov, Evgeny, Stasyuk, Elena, Rogov, Alexander, Varlamova, Natalya, Zelchan, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438322/
https://www.ncbi.nlm.nih.gov/pubmed/32814811
http://dx.doi.org/10.1038/s41598-020-70991-2
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author Sadkin, Vladimir
Sкuridin, Viktor
Nesterov, Evgeny
Stasyuk, Elena
Rogov, Alexander
Varlamova, Natalya
Zelchan, Roman
author_facet Sadkin, Vladimir
Sкuridin, Viktor
Nesterov, Evgeny
Stasyuk, Elena
Rogov, Alexander
Varlamova, Natalya
Zelchan, Roman
author_sort Sadkin, Vladimir
collection PubMed
description The work considers the problem of obtaining nanocolloid radiopharmaceuticals (RPs) and studying their functional suitability for diagnosing sentinel lymph nodes (SLN) in cancer patients. Two principal approaches to the formation of technetium-99m-labeled particles based on inorganic and organic matrices were considered when carrying out research to develop methods for the production of nanocolloid RPs. The composition of the reagents and the conditions for obtaining nanocolloid radiopharmaceuticals were determined. The functional suitability of new RPs for scintigraphic diagnostics of sentinel lymph nodes has been studied.
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spelling pubmed-74383222020-08-21 (99m)Tc-labeled nanocolloid drugs: development methods Sadkin, Vladimir Sкuridin, Viktor Nesterov, Evgeny Stasyuk, Elena Rogov, Alexander Varlamova, Natalya Zelchan, Roman Sci Rep Article The work considers the problem of obtaining nanocolloid radiopharmaceuticals (RPs) and studying their functional suitability for diagnosing sentinel lymph nodes (SLN) in cancer patients. Two principal approaches to the formation of technetium-99m-labeled particles based on inorganic and organic matrices were considered when carrying out research to develop methods for the production of nanocolloid RPs. The composition of the reagents and the conditions for obtaining nanocolloid radiopharmaceuticals were determined. The functional suitability of new RPs for scintigraphic diagnostics of sentinel lymph nodes has been studied. Nature Publishing Group UK 2020-08-19 /pmc/articles/PMC7438322/ /pubmed/32814811 http://dx.doi.org/10.1038/s41598-020-70991-2 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sadkin, Vladimir
Sкuridin, Viktor
Nesterov, Evgeny
Stasyuk, Elena
Rogov, Alexander
Varlamova, Natalya
Zelchan, Roman
(99m)Tc-labeled nanocolloid drugs: development methods
title (99m)Tc-labeled nanocolloid drugs: development methods
title_full (99m)Tc-labeled nanocolloid drugs: development methods
title_fullStr (99m)Tc-labeled nanocolloid drugs: development methods
title_full_unstemmed (99m)Tc-labeled nanocolloid drugs: development methods
title_short (99m)Tc-labeled nanocolloid drugs: development methods
title_sort (99m)tc-labeled nanocolloid drugs: development methods
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438322/
https://www.ncbi.nlm.nih.gov/pubmed/32814811
http://dx.doi.org/10.1038/s41598-020-70991-2
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