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Acylacetylenes in multiple functionalization of hydroxyquinolines and quinolones

The expected one-pot multiple functionalization of hydroxyquinolines and quinolones with acylacetylenes (20 mol% KOH, 5 equiv. H(2)O, MeCN, 55–60 °C), which, according to the previous finding, might involve the addition of OH and NH-functions to the triple bond and insertion of acylacetylenes into t...

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Detalles Bibliográficos
Autores principales: Belyaeva, Kseniya V., Nikitina, Lina P., Afonin, Andrei V., Trofimov, Boris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438341/
https://www.ncbi.nlm.nih.gov/pubmed/32839627
http://dx.doi.org/10.1016/j.tet.2020.131523