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Association of Genetic Variants at TRPC6 With Chemotherapy-Related Heart Failure

Background: Our previous GWAS identified genetic variants at six novel loci that were associated with a decline in left ventricular ejection fraction (LVEF), p < 1 × 10(−5) in 1,191 early breast cancer patients from the N9831 clinical trial of chemotherapy plus trastuzumab. In this study we sough...

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Detalles Bibliográficos
Autores principales: Norton, Nadine, Crook, Julia E., Wang, Liwei, Olson, Janet E., Kachergus, Jennifer M., Serie, Daniel J., Necela, Brian M., Borgman, Paul G., Advani, Pooja P., Ray, Jordan C., Landolfo, Carolyn, Di Florio, Damian N., Hill, Anneliese R., Bruno, Katelyn A., Fairweather, DeLisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438395/
https://www.ncbi.nlm.nih.gov/pubmed/32903434
http://dx.doi.org/10.3389/fcvm.2020.00142