MicroRNA-377-3p released by mesenchymal stem cell exosomes ameliorates lipopolysaccharide-induced acute lung injury by targeting RPTOR to induce autophagy

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the severe lung damage and respiratory failure without effective therapy. However, there was a lack of understanding of the mechanism by which exosomes regulate autophagy during ALI/ARDS. Here, we found lipopolysaccharide (LP...

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Detalles Bibliográficos
Autores principales: Wei, Xuxia, Yi, Xiaomeng, Lv, Haijin, Sui, Xin, Lu, Pinglan, Li, Lijuan, An, Yuling, Yang, Yang, Yi, Huimin, Chen, Guihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438519/
https://www.ncbi.nlm.nih.gov/pubmed/32814765
http://dx.doi.org/10.1038/s41419-020-02857-4

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