Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells

Colorectal cancer (CRC) is a leading cause of cancer death. Chemoresistance is a pivotal feature of cancer cells leading to treatment failure and ATP-binding cassette (ABC) transporters are responsible for the efflux of several molecules, including anticancer drugs. The Hedgehog-GLI (HH-GLI) pathway...

Descripción completa

Detalles Bibliográficos
Autores principales: Po, Agnese, Citarella, Anna, Catanzaro, Giuseppina, Besharat, Zein Mersini, Trocchianesi, Sofia, Gianno, Francesca, Sabato, Claudia, Moretti, Marta, De Smaele, Enrico, Vacca, Alessandra, Fiori, Micol Eleonora, Ferretti, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438531/
https://www.ncbi.nlm.nih.gov/pubmed/32814794
http://dx.doi.org/10.1038/s41598-020-70871-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438531/
https://www.ncbi.nlm.nih.gov/pubmed/32814794
http://dx.doi.org/10.1038/s41598-020-70871-9

Ejemplares similares