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Engineering Immune Cells for in vivo Secretion of Tumor-Specific T Cell-Redirecting Bispecific Antibodies

Immunotherapeutic approaches based on the redirection of T cell activity toward tumor cells are actively being investigated. The impressive clinical success of the continuously intravenously infused T cell-redirecting bispecific antibody (T-bsAb) blinatumomab (anti-CD19 x anti-CD3), and of engineere...

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Detalles Bibliográficos
Autores principales:	Blanco, Belén, Ramírez-Fernández, Ángel, Alvarez-Vallina, Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438551/ https://www.ncbi.nlm.nih.gov/pubmed/32903593 http://dx.doi.org/10.3389/fimmu.2020.01792

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