Rofecoxib Attenuates the Pathogenesis of Amyotrophic Lateral Sclerosis by Alleviating Cyclooxygenase-2-Mediated Mechanisms

Cyclooxygenase-2 (COX-2) is reported to be activated during the course of amyotrophic lateral sclerosis (ALS) development and progression. However, the roles of COX-2 in aggravating ALS and the underlying mechanism have been largely overlooked. To reveal the mechanisms, the canonical SOD1(G93A) mous...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Yan-Hui, Guan, Pei-Pei, Zhang, Shen-Qing, Guo, Yan-Su, Wang, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438558/
https://www.ncbi.nlm.nih.gov/pubmed/32903591
http://dx.doi.org/10.3389/fnins.2020.00817

Ejemplares similares

Ejemplares similares