Cargando…

Uncovering the Mechanisms of Cryptotanshinone as a Therapeutic Agent Against Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a fatal and dominant form of liver cancer that currently has no effective treatment or positive prognosis. In this study, we explored the antitumor effects of cryptotanshinone (CPT) against HCC and the molecular mechanisms underlying these effects using a systems ph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Yi, Song, Lei, Wang, Xinyu, Huang, Yujie, Liu, Yongqiang, Wang, Qi, Hong, Ming, Yuan, Zhongyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438559/ https://www.ncbi.nlm.nih.gov/pubmed/32903546 http://dx.doi.org/10.3389/fphar.2020.01264

Ejemplares similares

Novel perspectives on the therapeutic role of cryptotanshinone in the management of stem cell behaviors for high-incidence diseases
por: Guo, Xiaomeng, et al.
Publicado: (2022)

Synergistic Effects of Cryptotanshinone and Senkyunolide I in Guanxinning Tablet Against Endogenous Thrombus Formation in Zebrafish
por: Li, Jun, et al.
Publicado: (2021)

Integrated Proteomics and Metabolomics Link Acne to the Action Mechanisms of Cryptotanshinone Intervention
por: Zhu, Zhaoming, et al.
Publicado: (2021)

Preparation and optimization of surface stabilized cryptotanshinone nanocrystals with enhanced bioavailability
por: Zhao, Wenzheng, et al.
Publicado: (2023)

Anticancer potential of cryptotanshinone on breast cancer treatment; A narrative review
por: Dalil, Davood, et al.
Publicado: (2022)

Pharmacokinetics and tissue distribution of bleomycin-induced idiopathic pulmonary fibrosis rats treated with cryptotanshinone
por: He, Xiangjun, et al.
Publicado: (2023)

Cryptotanshinone Is a Intervention for ER-Positive Breast Cancer: An Integrated Approach to the Study of Natural Product Intervention Mechanisms
por: Li, Huayao, et al.
Publicado: (2021)

Cryptotanshinone Inhibits the Growth of HCT116 Colorectal Cancer Cells Through Endoplasmic Reticulum Stress-Mediated Autophagy
por: Fu, Xiaojing, et al.
Publicado: (2021)

Comparative Proteomics Analysis Reveals the Reversal Effect of Cryptotanshinone on Gefitinib-Resistant Cells in Epidermal Growth Factor Receptor-Mutant Lung Cancer
por: Cai, Peiheng, et al.
Publicado: (2022)

Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis
por: Guo, Keke, et al.
Publicado: (2022)

Cryptotanshinone Attenuates Airway Remodeling by Inhibiting Crosstalk Between Tumor Necrosis Factor-Like Weak Inducer of Apoptosis and Transforming Growth Factor Beta 1 Signaling Pathways in Asthma
por: Wang, Chongyang, et al.
Publicado: (2019)

Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
por: Hosokawa, Motoyasu, et al.
Publicado: (2023)

Uncovering the Anticancer Mechanisms of Chinese Herbal Medicine Formulas: Therapeutic Alternatives for Liver Cancer
por: Chen, Feiyu, et al.
Publicado: (2020)

Alkaloid from Alstonia yunnanensis diels root against gastrointestinal cancer: Acetoxytabernosine inhibits apoptosis in hepatocellular carcinoma cells
por: Lai, Qi, et al.
Publicado: (2023)

Integrated investigation and experimental validation of PPARG as an oncogenic driver: implications for prognostic assessment and therapeutic targeting in hepatocellular carcinoma
por: Ran, Yunsheng, et al.
Publicado: (2023)

Integrated comparative metabolomics and network pharmacology approach to uncover the key active ingredients of Polygonati rhizoma and their therapeutic potential for the treatment of Alzheimer’s disease
por: Wang, Fu, et al.
Publicado: (2022)

Disruption of PD-1 Enhanced the Anti-tumor Activity of Chimeric Antigen Receptor T Cells Against Hepatocellular Carcinoma
por: Guo, Xingliang, et al.
Publicado: (2018)

Cryptotanshinone affects HFL-1 cells proliferation by inhibiting cytokines secretion in RAW264.7 cells and ameliorates inflammation and fibrosis in newborn rats with hyperoxia induced lung injury
por: Ma, Mengmeng, et al.
Publicado: (2023)

Immunotherapies for advanced hepatocellular carcinoma
por: Sun, Li-Yang, et al.
Publicado: (2023)

The Therapeutic Efficacy and Safety of Compound Kushen Injection Combined with Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma: An Update Systematic Review and Meta-Analysis
por: Ma, Xiao, et al.
Publicado: (2016)

Drug resistance mechanism of kinase inhibitors in the treatment of hepatocellular carcinoma
por: Jiang, Lei, et al.
Publicado: (2023)

Uncovering the pharmacological mechanisms of Zizhu ointment against diabetic ulcer by integrating network analysis and experimental evaluation in vivo and in vitro
por: Wang, Jie, et al.
Publicado: (2022)

Therapeutic Potentials of Selected Antihypertensive Agents and Their Fixed-Dose Combinations Against Trastuzumab-Mediated Cardiotoxicity
por: Olorundare, Olufunke Esan, et al.
Publicado: (2021)

Investigating the effect of Icaritin on hepatocellular carcinoma based on network pharmacology
por: Xue, Zhong, et al.
Publicado: (2023)

Functional oral nanoparticles for delivering silibinin and cryptotanshinone against breast cancer lung metastasis
por: Liu, Ying, et al.
Publicado: (2020)

Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis
por: Ji, Quanbo, et al.
Publicado: (2018)

Targeted Therapeutic Strategies in the Battle Against Pathogenic Bacteria
por: Yang, Bingqing, et al.
Publicado: (2021)

The role of RNA modification in hepatocellular carcinoma
por: Feng, Qiang, et al.
Publicado: (2022)

Herb-Drug Interaction Between Xiyanping Injection and Lopinavir/Ritonavir, Two Agents Used in COVID-19 Pharmacotherapy
por: Ye, Linhu, et al.
Publicado: (2021)

Heterogeneity characterization of hepatocellular carcinoma based on the sensitivity to 5-fluorouracil and development of a prognostic regression model
por: Gu, Xinyu, et al.
Publicado: (2023)

Review of the Efficacy and Mechanisms of Traditional Chinese Medicines as a Therapeutic Option for Ionizing Radiation Induced Damage
por: Zhang, Xiaomeng, et al.
Publicado: (2021)

Pharmacological properties, molecular mechanisms and therapeutic potential of ginsenoside Rg3 as an antioxidant and anti-inflammatory agent
por: Wang, Jing, et al.
Publicado: (2022)

Editorial: Protein-based nanocarriers for delivery of nutraceutical, diagnostic and therapeutic agents
por: Zhong, Jian, et al.
Publicado: (2022)

Therapeutic Agents for the Treatment of Temporomandibular Joint Disorders: Progress and Perspective
por: Wu, Mengjie, et al.
Publicado: (2021)

Cryptotanshinone induces ROS-mediated apoptosis in human gastric cancer cells
por: Liu, Chang, et al.
Publicado: (2017)

The Influence of Selected Factors on the Aqueous Cryptotanshinone Solubility
por: Kobryń, Justyna, et al.
Publicado: (2021)

Efferocytosis signatures as prognostic markers for revealing immune landscape and predicting immunotherapy response in hepatocellular carcinoma
por: Xu, Ke, et al.
Publicado: (2023)

Resveratrol—Potential Antibacterial Agent against Foodborne Pathogens
por: Ma, Dexter S. L., et al.
Publicado: (2018)

The role of NLRP3 inflammasome in hepatocellular carcinoma
por: Zhao, Huijie, et al.
Publicado: (2023)

Roles of hypoxia-inducible factor in hepatocellular carcinoma under local ablation therapies
por: Xiao, Chunying, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5dpnp9trjosdhovrqv36lg02jc