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Complement Activation by C-Reactive Protein Is Critical for Protection of Mice Against Pneumococcal Infection

C-reactive protein (CRP), a component of the innate immune system, is an antipneumococcal plasma protein. Human CRP has been shown to protect mice against infection with lethal doses of Streptococcus pneumoniae by decreasing bacteremia. in vitro, CRP binds to phosphocholine-containing substances, su...

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Detalles Bibliográficos
Autores principales: Singh, Sanjay K., Ngwa, Donald N., Agrawal, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438579/
https://www.ncbi.nlm.nih.gov/pubmed/32903624
http://dx.doi.org/10.3389/fimmu.2020.01812

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