Estradiol Replacement at the Critical Period Protects Hippocampal Neural Stem Cells to Improve Cognition in APP/PS1 Mice

It has been suggested that there is a critical window for estrogen replacement therapy (ERT) in postmenopausal women with Alzheimer’s disease (AD); however, supporting evidence is lacking. To address this issue, we investigated the effective period for estradiol (E2) treatment using a mouse model of...

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Detalles Bibliográficos
Autores principales: Qin, Yaoyao, An, Dong, Xu, Weixing, Qi, Xiuting, Wang, Xiaoli, Chen, Ling, Chen, Lei, Sha, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438824/
https://www.ncbi.nlm.nih.gov/pubmed/32903757
http://dx.doi.org/10.3389/fnagi.2020.00240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438824/
https://www.ncbi.nlm.nih.gov/pubmed/32903757
http://dx.doi.org/10.3389/fnagi.2020.00240

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