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Overexpression of TIGIT in NK and T Cells Contributes to Tumor Immune Escape in Myelodysplastic Syndromes

OBJECTIVE: Targeting immune checkpoints, such as PD-1, represents a promising approach for cancer immunotherapy, achieving long-term disease remission rates in numerous types of cancer. T cell immunoglobulin and ITIM domain (TIGIT) is a checkpoint receptor associated with the antitumor roles of NK a...

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Detalles Bibliográficos
Autores principales:	Meng, Fanqiao, Li, Lijuan, Lu, Fengzhu, Yue, Jing, Liu, Zhaoyun, Zhang, Wei, Fu, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438899/ https://www.ncbi.nlm.nih.gov/pubmed/32903786 http://dx.doi.org/10.3389/fonc.2020.01595

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