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Eye Drops of Metformin Prevents Fibrosis After Glaucoma Filtration Surgery in Rats via Activating AMPK/Nrf2 Signaling Pathway

Metformin has effective therapeutic effects in anti-tumor and anti-fibrotic diseases. However, how the antifibrotic effect of metformin in the eye and how it is transferred are still unclear. Here, the eye drop of metformin treatment was studied in Sprague–Dawley (SD) rats of glaucoma filtrating sur...

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Detalles Bibliográficos
Autores principales:	Li, Xueru, Leng, Yu, Jiang, Qingzhi, Wang, Ziwen, Luo, Peng, Zhang, Chi, Chen, Long, Wang, Yawei, Wang, Huilan, Yue, Xiaofeng, Shen, Chongxing, Zhou, Yuanlinhan, Shi, Chunmeng, Xie, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438907/ https://www.ncbi.nlm.nih.gov/pubmed/32903813 http://dx.doi.org/10.3389/fphar.2020.01038

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