Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer’s Disease

Nicotinamide (vitamin B3) is a key component in the cellular production of Nicotinamide Adenine Dinucleotide (NAD) and has long been associated with neuronal development, survival and death. Numerous data suggest that nicotinamide may offer therapeutic benefits in neurodegenerative disorders, includ...

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Detalles Bibliográficos
Autores principales: Salech, Felipe, Ponce, Daniela P., Paula-Lima, Andrea C., SanMartin, Carol D., Behrens, María I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438969/
https://www.ncbi.nlm.nih.gov/pubmed/32903806
http://dx.doi.org/10.3389/fnagi.2020.00255

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