Cargando…

There is no intraocular affection on a SARS-CoV-2 - Infected ocular surface

PURPOSE: The presence of SARS-CoV-2 RNA in anterior chamber fluid and/or the vitreous in patients with SARS-CoV-2 RNA on the ocular surface is unclear. Knowledge about the infectious state of intraocular structures could influence the daily work of ophthalmic surgeons. OBSERVATIONS: We analyzed ocul...

Descripción completa

Detalles Bibliográficos
Autores principales: Lauermann, Peer, Storch, Marcus, Weig, Michael, Tampe, Björn, Winkler, Martin, Hoerauf, Hans, Feltgen, Nicolas, Hakroush, Samy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439011/
https://www.ncbi.nlm.nih.gov/pubmed/32839739
http://dx.doi.org/10.1016/j.ajoc.2020.100884
_version_ 1783572908665208832
author Lauermann, Peer
Storch, Marcus
Weig, Michael
Tampe, Björn
Winkler, Martin
Hoerauf, Hans
Feltgen, Nicolas
Hakroush, Samy
author_facet Lauermann, Peer
Storch, Marcus
Weig, Michael
Tampe, Björn
Winkler, Martin
Hoerauf, Hans
Feltgen, Nicolas
Hakroush, Samy
author_sort Lauermann, Peer
collection PubMed
description PURPOSE: The presence of SARS-CoV-2 RNA in anterior chamber fluid and/or the vitreous in patients with SARS-CoV-2 RNA on the ocular surface is unclear. Knowledge about the infectious state of intraocular structures could influence the daily work of ophthalmic surgeons. OBSERVATIONS: We analyzed ocular samples from a patient who had succumbed to COVID-19 pneumonia for the prevalence of SARS-CoV-2 RNA. We detected viral RNA in the ocular-surface samples on one swab and in one excidate from the conjunctiva. Samples from the anterior chamber and vitreous revealed no SARS-CoV-2 RNA. CONCLUSIONS: SARS-CoV-2 can effectively be inactivated with standard disinfection agents. The now proven absence of SARS-CoV-2 in intraocular fluids could influence how ophthalmic surgeons work. Without having to account for the risk of a contagion via the anterior chamber and/or vitreous body, the surgical staff would require no additional, more elaborate protection.
format Online
Article
Text
id pubmed-7439011
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-74390112020-08-20 There is no intraocular affection on a SARS-CoV-2 - Infected ocular surface Lauermann, Peer Storch, Marcus Weig, Michael Tampe, Björn Winkler, Martin Hoerauf, Hans Feltgen, Nicolas Hakroush, Samy Am J Ophthalmol Case Rep Case Report PURPOSE: The presence of SARS-CoV-2 RNA in anterior chamber fluid and/or the vitreous in patients with SARS-CoV-2 RNA on the ocular surface is unclear. Knowledge about the infectious state of intraocular structures could influence the daily work of ophthalmic surgeons. OBSERVATIONS: We analyzed ocular samples from a patient who had succumbed to COVID-19 pneumonia for the prevalence of SARS-CoV-2 RNA. We detected viral RNA in the ocular-surface samples on one swab and in one excidate from the conjunctiva. Samples from the anterior chamber and vitreous revealed no SARS-CoV-2 RNA. CONCLUSIONS: SARS-CoV-2 can effectively be inactivated with standard disinfection agents. The now proven absence of SARS-CoV-2 in intraocular fluids could influence how ophthalmic surgeons work. Without having to account for the risk of a contagion via the anterior chamber and/or vitreous body, the surgical staff would require no additional, more elaborate protection. Elsevier 2020-08-20 /pmc/articles/PMC7439011/ /pubmed/32839739 http://dx.doi.org/10.1016/j.ajoc.2020.100884 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Lauermann, Peer
Storch, Marcus
Weig, Michael
Tampe, Björn
Winkler, Martin
Hoerauf, Hans
Feltgen, Nicolas
Hakroush, Samy
There is no intraocular affection on a SARS-CoV-2 - Infected ocular surface
title There is no intraocular affection on a SARS-CoV-2 - Infected ocular surface
title_full There is no intraocular affection on a SARS-CoV-2 - Infected ocular surface
title_fullStr There is no intraocular affection on a SARS-CoV-2 - Infected ocular surface
title_full_unstemmed There is no intraocular affection on a SARS-CoV-2 - Infected ocular surface
title_short There is no intraocular affection on a SARS-CoV-2 - Infected ocular surface
title_sort there is no intraocular affection on a sars-cov-2 - infected ocular surface
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439011/
https://www.ncbi.nlm.nih.gov/pubmed/32839739
http://dx.doi.org/10.1016/j.ajoc.2020.100884
work_keys_str_mv AT lauermannpeer thereisnointraocularaffectiononasarscov2infectedocularsurface
AT storchmarcus thereisnointraocularaffectiononasarscov2infectedocularsurface
AT weigmichael thereisnointraocularaffectiononasarscov2infectedocularsurface
AT tampebjorn thereisnointraocularaffectiononasarscov2infectedocularsurface
AT winklermartin thereisnointraocularaffectiononasarscov2infectedocularsurface
AT hoeraufhans thereisnointraocularaffectiononasarscov2infectedocularsurface
AT feltgennicolas thereisnointraocularaffectiononasarscov2infectedocularsurface
AT hakroushsamy thereisnointraocularaffectiononasarscov2infectedocularsurface