AURKA Increase the Chemosensitivity of Colon Cancer Cells to Oxaliplatin by Inhibiting the TP53-Mediated DNA Damage Response Genes

AURKA, a cell cycle-regulated kinase, is associated with malignant transformation and progression in many cancer types. We analyzed the expression change of AURKA in pan-cancer and its effect on the prognosis of cancer patients using the TCGA dataset. We revealed that AURKA was extensively elevated...

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Detalles Bibliográficos
Autores principales: Shan, Baocong, Zhao, Ran, Zhou, Jian, Zhang, Minghui, Qi, Xiaoyu, Wang, Tianzhen, Gong, Jinan, Wu, Yiqi, Zhu, Yuanyuan, Yang, Weiwei, Zhang, Yang, Wang, Guangyou, Li, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439175/
https://www.ncbi.nlm.nih.gov/pubmed/32851091
http://dx.doi.org/10.1155/2020/8916729

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