Elamipretide Attenuates Pyroptosis and Perioperative Neurocognitive Disorders in Aged Mice

Pyroptosis is a recently characterized inflammatory form of programmed cell death that is thought to be involved in the pathogenesis of perioperative neurocognitive disorders (PND). Elamipretide (SS-31), a mitochondrial-targeted peptide with multiple pharmacological properties, including anti-inflam...

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Detalles Bibliográficos
Autores principales: Zuo, Youmei, Yin, Lei, Cheng, Xinqi, Li, Jun, Wu, Hao, Liu, Xuesheng, Gu, Erwei, Wu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439217/
https://www.ncbi.nlm.nih.gov/pubmed/32903868
http://dx.doi.org/10.3389/fncel.2020.00251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439217/
https://www.ncbi.nlm.nih.gov/pubmed/32903868
http://dx.doi.org/10.3389/fncel.2020.00251

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