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Elamipretide Attenuates Pyroptosis and Perioperative Neurocognitive Disorders in Aged Mice
Pyroptosis is a recently characterized inflammatory form of programmed cell death that is thought to be involved in the pathogenesis of perioperative neurocognitive disorders (PND). Elamipretide (SS-31), a mitochondrial-targeted peptide with multiple pharmacological properties, including anti-inflam...
Autores principales: | Zuo, Youmei, Yin, Lei, Cheng, Xinqi, Li, Jun, Wu, Hao, Liu, Xuesheng, Gu, Erwei, Wu, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439217/ https://www.ncbi.nlm.nih.gov/pubmed/32903868 http://dx.doi.org/10.3389/fncel.2020.00251 |
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