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Physicochemical Characterization, Molecular Docking, and In Vitro Dissolution of Glimepiride–Captisol Inclusion Complexes

[Image: see text] This present study investigated the effect of Captisol, a chemically modified cyclodextrin, on the in vitro dissolution of glimepiride. We prepared glimepiride–Captisol complexes of different mass ratios (1:1, 1:2, and 1:3 w/w) by a physical mixing or freeze-drying technique, and f...

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Detalles Bibliográficos
Autores principales: Pal, Arpita, Roy, Sudeep, Kumar, Akhil, Mahmood, Syed, Khodapanah, Nasrin, Thomas, Sabu, Agatemor, Christian, Ghosal, Kajal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439272/
https://www.ncbi.nlm.nih.gov/pubmed/32832751
http://dx.doi.org/10.1021/acsomega.0c01228