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Crystal structure of the human oxytocin receptor

The peptide hormone oxytocin modulates socioemotional behavior and sexual reproduction via the centrally expressed oxytocin receptor (OTR) across several species. Here, we report the crystal structure of human OTR in complex with retosiban, a nonpeptidic antagonist developed as an oral drug for the...

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Detalles Bibliográficos
Autores principales:	Waltenspühl, Yann, Schöppe, Jendrik, Ehrenmann, Janosch, Kummer, Lutz, Plückthun, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439316/ https://www.ncbi.nlm.nih.gov/pubmed/32832646 http://dx.doi.org/10.1126/sciadv.abb5419

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