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Phenotype stability under dynamic brain-tumor environment stimuli maps glioblastoma progression in patients

Although tumor invasiveness is known to drive glioblastoma (GBM) recurrence, current approaches to treatment assume a fairly simple GBM phenotype transition map. We provide new analyses to estimate the likelihood of reaching or remaining in a phenotype under dynamic, physiologically likely perturbat...

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Detalles Bibliográficos
Autores principales: Rajapakse, Vinodh N., Herrada, Sylvia, Lavi, Orit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439317/
https://www.ncbi.nlm.nih.gov/pubmed/32832595
http://dx.doi.org/10.1126/sciadv.aaz4125