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Phenotype stability under dynamic brain-tumor environment stimuli maps glioblastoma progression in patients
Although tumor invasiveness is known to drive glioblastoma (GBM) recurrence, current approaches to treatment assume a fairly simple GBM phenotype transition map. We provide new analyses to estimate the likelihood of reaching or remaining in a phenotype under dynamic, physiologically likely perturbat...
Autores principales: | Rajapakse, Vinodh N., Herrada, Sylvia, Lavi, Orit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439317/ https://www.ncbi.nlm.nih.gov/pubmed/32832595 http://dx.doi.org/10.1126/sciadv.aaz4125 |
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