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An enzymatic on/off switch‐mediated assay for KRAS hotspot point mutation detection of circulating tumor DNA
BACKGROUND: To detect the mutations of KRAS gene in colorectal cancer patients and other cancer patients, it is of value to develop non‐invasive, sensitive, specific, easy, and low‐cost assays. METHODS: Templates harboring hotspot mutations of the KRAS gene were constructed, and primers were designe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439329/ https://www.ncbi.nlm.nih.gov/pubmed/32207862 http://dx.doi.org/10.1002/jcla.23305 |