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Synthesis of the Novel AT(1) Receptor Tracer [(18)F]Fluoropyridine–Candesartan via Click Chemistry

[Image: see text] A novel 7-((4-(3-((2-[(18)F]fluoropyridin-3-yl)oxy)propyl)-1H-1,2,3-triazol-1-yl)methyl)-1H-benzo[d]imidazole derivative of the angiotensin II type-1 receptor (AT(1)R) blocker candesartan, [(18)F]fluoropyridine–candesartan, was synthesized via the copper-catalyzed azide–alkyne cycl...

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Detalles Bibliográficos
Autores principales: Abreu Diaz, Aida M., Drumeva, Gergana O., Petrenyov, Daniil R., Carrier, Jean-François, DaSilva, Jean N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439361/
https://www.ncbi.nlm.nih.gov/pubmed/32832788
http://dx.doi.org/10.1021/acsomega.0c02310