Elevated ACE-2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-CoV-2 entry and replication

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ACE2 protein is expressed at high levels in the human olfactory epithelium relative to upper airway epithelial cells. This may explain COVID-19-associated olfactory dysfunction, and suggests a SARS-CoV-2 reservoir site and potential intranasal therapy. https://bit.ly/3hxT0qm

Detalles Bibliográficos
Autores principales: Chen, Mengfei, Shen, Wenjuan, Rowan, Nicholas R., Kulaga, Heather, Hillel, Alexander, Ramanathan, Murugappan, Lane, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Agora
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439429/
https://www.ncbi.nlm.nih.gov/pubmed/32817004
http://dx.doi.org/10.1183/13993003.01948-2020
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