Gcn5p and Ubp8p Affect Protein Ubiquitylation and Cell Proliferation by Altering the Fermentative/Respiratory Flux Balance in Saccharomyces cerevisiae

Protein ubiquitylation regulates not only endocellular trafficking and proteasomal degradation but also the catalytic activity of enzymes. In Saccharomyces cerevisiae, we analyzed the composition of the ubiquitylated proteomes in strains lacking acetyltransferase Gcn5p, Ub-protease Ubp8p, or both to...

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Detalles Bibliográficos
Autores principales: De Palma, Antonella, Fanelli, Giulia, Cretella, Elisabetta, De Luca, Veronica, Palladino, Raffaele Antonio, Panzeri, Valentina, Roffia, Valentina, Saliola, Michele, Mauri, Pierluigi, Filetici, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439465/
https://www.ncbi.nlm.nih.gov/pubmed/32788380
http://dx.doi.org/10.1128/mBio.01504-20

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