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Three Related Enzymes in Candida albicans Achieve Arginine- and Agmatine-Dependent Metabolism That Is Essential for Growth and Fungal Virulence
Amino acid metabolism is crucial for fungal growth and development. Ureohydrolases produce amines when acting on l-arginine, agmatine, and guanidinobutyrate (GB), and these enzymes generate ornithine (by arginase), putrescine (by agmatinase), or GABA (by 4-guanidinobutyrase or GBase). Candida albica...
Autores principales: | Schaefer, Katja, Wagener, Jeanette, Ames, Ryan M., Christou, Stella, MacCallum, Donna M., Bates, Steven, Gow, Neil A. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439472/ https://www.ncbi.nlm.nih.gov/pubmed/32788384 http://dx.doi.org/10.1128/mBio.01845-20 |
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