SPP1 promotes Schwann cell proliferation and survival through PKCα by binding with CD44 and αvβ3 after peripheral nerve injury

BACKGROUND: Schwann cells (SCs) play a crucial role in Wallerian degeneration after peripheral nerve injury. The expression of genes in SCs undergo a series of changes, which greatly affect the proliferation and apoptosis of SCs as well as the fate of peripheral nerve regeneration. However, how do t...

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Detalles Bibliográficos
Autores principales: Wang, Jiang-Bo, Zhang, Zhan, Li, Jian-Nan, Yang, Tuo, Du, Shuang, Cao, Rang-Juan, Cui, Shu-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439540/
https://www.ncbi.nlm.nih.gov/pubmed/32843960
http://dx.doi.org/10.1186/s13578-020-00458-4

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