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Simvastatin induces adverse effects on proliferation and mineralization of human primary osteoblasts

BACKGROUND: Frequently statins were administered to reduce the LDL-concentration in circulating blood. Especially simvastatin (SV) is an often prescribed statin. Pleiotropic effects of these drugs were reported. Thus, the aim of this study was to evaluate effects of SV on osteoblastic mineralization...

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Detalles Bibliográficos
Autores principales: Sabandal, Martin Mariano Isabelo, Schäfer, Edgar, Aed, Jonathan, Jung, Susanne, Kleinheinz, Johannes, Sielker, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439668/
https://www.ncbi.nlm.nih.gov/pubmed/32819403
http://dx.doi.org/10.1186/s13005-020-00232-4

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