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Simvastatin induces adverse effects on proliferation and mineralization of human primary osteoblasts
BACKGROUND: Frequently statins were administered to reduce the LDL-concentration in circulating blood. Especially simvastatin (SV) is an often prescribed statin. Pleiotropic effects of these drugs were reported. Thus, the aim of this study was to evaluate effects of SV on osteoblastic mineralization...
Autores principales: | Sabandal, Martin Mariano Isabelo, Schäfer, Edgar, Aed, Jonathan, Jung, Susanne, Kleinheinz, Johannes, Sielker, Sonja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439668/ https://www.ncbi.nlm.nih.gov/pubmed/32819403 http://dx.doi.org/10.1186/s13005-020-00232-4 |
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